Nestled in a serene sanctuary overlooking the Isinglass River, this spectacular 2-acre property offers the perfect blend of luxury, comfort, and nature, all within a short 15-minute drive to downtown Dover. The meticulously maintained home boasts over 4,400 sf of finished living area, providing both private retreats and inviting communal spaces, perfect for relaxation, entertaining and home offices. 1st-floor primary features river views, a gas fireplace and spacious ensuite bath. Pet lovers will appreciate the dedicated dog washroom, ideal for those wanting furry friends clean after a fun day outdoors. The low maintenance exterior gives you more time to enjoy the things you love. An oversized 2-car garage provides direct access to the kitchen and basement. A heated 3-car detached garage with walk-up 2nd floor is perfect for a car collector, hobbyist, artist, or anyone who just wants more storage or workspace. Outdoor living is an added bonus, with three riverside decks designed to enjoy abundant nature and flowing waters below. Anglers will be in heaven just steps away from year-round stocked trout fishing. Includes ownership in the adjacent 3.9 ac. waterfront lot. Minutes from all major highways and the vibrant downtowns of Dover and Portsmouth, this home offers the perfect balance of seclusion and convenience. You'll enjoy the peace and privacy of rural living while being close to shopping, restaurants, top-rated schools and first-class medical facilities.